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alpha-fetoprotein

Bible DictionaryNCI Dictionary of Cancer Terms
[AL-fa-FEE-toe-PRO-teen]AFP. A protein normally produced by a fetus. AFP levels are usually undetectable in the blood of healthy adult men or women (who are not pregnant). An elevated level of AFP suggests the presence of either a primary liver cancer or germ cell tumor. 
A Service of the National Cancer Institute.
Bible DictionaryGlossary for Testicular Cancer
AFP is a protein found in the bloodstream of some men with testicular cancer. The level rises when the cancer is growing and falls when the cancer is shrinking or has been surgically removed, so a blood test can possibly measure the progress of the disease and success of treatment. Because of this behavior, it is referred to as a tumor marker. Elevated levels of AFP occur in 75 per cent of patients with teratocarcinomaembryonal cell carcinoma, and yolk sac carcinoma. (However, increased levels of AFP are also found in patients with liver diseases, such as cirrhosis, acute and chronic hepatitis and hepatic necrosis. ) The serum half life of AFP is 5 to 7 days, which implies that elevated levels of AFP should fall by one half of the initial level per week and should return to normal within 25 to 35 days after surgery if all of the tumor has been removed.
Bible DictionaryHepatitis Central (TM) Liver Disease Medical Glossary
A fetal blood protein present abnormally in adults with some forms of cancer, such as liver cancer&macr (alpha) Level--The probability of a false positive result, or of rejecting the hypothesis of no treatment difference when there is no real difference or of a false positive. Also referred to as the probability of a type I error &macr (alpha) Spending Function--A function or rule that governs how the total &macr level or probability of a type I error can be spread out over the interim analysis. Limits the chance of a false positive result when trial data is looked at multiple times. Can be used to set up guidelines for trial monitoring
Bible DictionaryDictionary of Medicine
nounprotein found in the amniotic fluid when the fetus has an open neurological deficiency such as meningomyelocele
Bible DictionaryRare Diseases Medical Terms
A protein excreted by the fetus into the amniotic fluid and from there into the mother's bloodstream through the placenta.

 

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