ZALCITABINE

a nucleoside analog drug that inhibits HIV replication by interfering with the reverse transcriptase enzyme. The drug is FDA-approved for the treatment of HIV disease; current practice favors use in combinations. Adverse side effects may include nausea, peripheral neuropathy, oral ulcers and pancreatitis.

A nucleoside reverse transcriptase inhibitor<!-- (see) --> first approved by FDA in 1992 and used in combination with antiretroviral agents<!-- (see) --> for the treatment of HIV infection in patients 13 years of age and older. Also called ddC, HIVID.

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