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GGTP (GAMMA-GT)

Bible DictionaryHepatitis Central (TM) Liver Disease Medical Glossary
Gamma-Glutamyl Transferase is markedly increased in lesions which cause intrahepatic or extrahepatic obstruction of bile ducts, including parenchymatous liver diseases with a major cholestatic component (e.g., cholestatic hepatitis). Lesser elevations of gamma-GT are seen in other liver diseases, and in infectious mononucleosis, hyperthyroidism, myotonic dystrophy, and after renal allograft. Drugs causing hepatocellular damage and cholestasis may also cause gamma-GT elevation. Gamma-GT is a very sensitive test for liver damage, and unexpected, unexplained mild elevations are common. Alcohol consumption is a common culprit. Decreased gamma-GT is not clinically significant

 

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