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DCCT

Bible DictionaryNDIC Diabetes Dictionary
see Diabetes Control and Complications Trial.  
 
a study by the National Institute of Diabetes and Digestive and Kidney Diseases, conducted from 1983 to 1993 in people with type 1 diabetes. The study showed that intensive therapy compared to conventional therapy significantly helped prevent or delay diabetes complications. Intensive therapy included multiple daily insulin injections or the use of an insulin pump with multiple blood glucose readings each day. Complications followed in the study included diabetic retinopathy, neuropathy, and nephropathy.  
Source: The National Diabetes Information Clearinghouse (NDIC), NIH Publication No. 07–3016, October 2006 (About)
Bible DictionaryDiabetes Glossary
A multicenter randomized clinical trial designed to test the hypothesis that tight control to maintain close-to-normal blood glucose profiles can delay or prevent diabetes's secondary complications. People between 13-39 with IDDM defined by impaired production of C-peptides were divided in two groups.and randomized to be treated with Conventional Therapy or Intensive Therapy. The Prevention group consisted of individuals with no evidence of severe diabetic complication and who have IDDM from 1-5 years. The Intervention group was constituted by individuals that had IDDM for 1-15 years and present mild complications. In general, results show that Intensive Therapy reduced risk of complications as well as the incidence of complications such as nephropathy , retinopathy and neuropathy in the prevention group. In the intervention group a slow in progression and reduce risk is patent except for neuropathy. Although the study was not designed to asses the impact on macrovascular disease, levels of cholesterol were lower with Intensive Therapy. The Intensive Therapy's side effects are mainly hypoglycimia and weight gain.

 

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